The Siamese
The following diseases are reported to occur more frequently in the Siamese than in the general cat population. In some cases the disease either has, or is believed to have, a genetic, hereditary cause but many of the diseases listed here do not have a proven genetic basis. 

If you do not find the disease that you are looking for in this list the disorder has probably not been reported to occur more frequently in this breed than in the cat population as a whole. Try to find it through the search button.

Alimentary tract diseases
This section includes diseases that involve the mouth, oesophagus (gullet), stomach, small intestine (duodenum and ileum), large intestine (colon and rectum), liver and pancreas.

Diseases involving the mouth

Diseases affecting the gullet (oesophagus)

Diseases involving the stomach
  • Gastric retention (pyloric)

Diseases involving the pancreas

Diseases affecting the small intestine

  • Adenocarcinoma

Diseases affecting the large intestine

Blood diseases


  • Adenocarcinoma (small intestine)
  • Basal cell tumour
  • Insulinoma
  • Intestinal adenocarcinoma
  • Lipoma
  • Mammary tumours
  • Mast cell tumours
  • Nasal cavity tumours
  • Parathyroid tumours
  • Sweat gland tumour

Cardiovascular diseases

Heart valve disorders

Abnormal development of major blood vessels to the heart

  • Patent ductus arteriosus

Heart muscle disease


  • Endocardial fibroelastosis
  • Persistent atrial standstill

Eye diseases

Diseases of the cornea

  • Corneal sequestration
Diseases of the eyeball
  • Convergent strabismus and nystagmus (congenital)
  • Glaucoma
  • Microphakia

Diseases of the eyelids

Diseases of the third eyelid (nictitating membrane)

Diseases of the lens

Diseases of the retina

  • Lysosomal storage diseasess, including :
    • Mucopolysaccharidosis VI (autosomal recessive)
  • Retinal degeneration

Hormonal diseases

  • Hyperparathyroidism (primary)
  • Insulinoma and hyperinsulinaemia

Immune system diseases

Liver diseases

Nervous system diseases

  • Deafness (congenital)
  • Hydrocephalus
  • Hypereaesthesia syndrome
  • Lysosomal storage diseases
    • ceroid lipofuscinosis
    • GM1 gangliosidosis (autosomal recessive)
    • Mucopolysaccharidosis VI (autosomal recessive)
    •  sphyngomyelinosis (autosomal recessive)
  • Myasthenia gravis (congenital)
  • Vestibular disease

Orthopaedic diseases

  • Hip dysplasia
  • Mucopolysaccharidosis VI (autosomal recessive)
  • Myasthenia gravis (congenital)
  • Nutritional secondary hyperparathyroidism

Respiratory diseases

Skin diseases

  • Aguirre syndrome
  • Blastomycosis
  • Cryptococcosis
  • Demodicosis (generalised)
  • Epidermolysis bullosa
  • Eyelid coloboma
  • Feline acromelanism
  • Food hypersensitivity
  • Histoplasmosis
  • Hypotrichosis (congenital) (autosomal recessive)
  • Junctional epidermolysis bullosa
  • Periocular leukotrichia
  • Pinnal alopecia
  • Psychogenic alopecia
  • Sporotrichosis
  • Skin tumours
  • Systemic lupus erythematosus
  • Tail sucking
  • Tuberculosis (cutaneous)
  • Vitiligo


  • Blastomycosis
  • Cryptococcus
  • Histoplasmosis
  • Mycobacterium avium
  • Reactions to griseofulvin

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