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This information is provided by
Provet for educational purposes only.
You should seek the advice of your
veterinarian if your pet is ill as only he or she can correctly advise on the
diagnosis and recommend the treatment that is most appropriate for your pet.
Corticosteroids (sometimes just
called "steroids") are some of the most commonly prescribed drugs
for veterinary patients...but what are they? Natural
corticosteroids are hormones produced by the adrenal glands, which are located
near to the kidneys. There are two types of corticosteroid :
- Glucocorticoids
- these affect the metabolism of the sugar glucose, but they also alter
protein and calcium metabolism. In addition they have anti-inflammatory
actions. They are the most commonly prescribed corticosteroids and they
are used in the management of many diseases from allergies to colitis, eye
diseases to cancer treatment and they are excellent in the treatment of
shock and as hormone replacement therapy in adrenal disease. Popular drugs
in this category include prednisolone, betamethasone, dexamethasone and
triamcinolone.
- Mineralocorticoids
- these affect water and electrolyte balance. These drugs are not used
that frequently. An example is fludrocortisone acetate which is used as
hormone replacement therapy in adrenal disease.
Corticosteroids play a very important role in
the treatment of many diseases, but there are some problems associated with
their use :
- There are many side-effects including
muscle wastage, delayed wound healing, increased thirst and hair loss.
- Sometimes treatment with
"steroids" can lead to the development of diabetes
- Sometimes treatment with
"steroids" can lead to failure of the adrenal glands to produce
hormones.
- They can cause abortion in pregnant
animals.
- They can cause ulcers in the
gastrointestinal tract - stomach or intestine.
- "Steroids" can reduce immunity
and make animals more susceptible to infections.
For this reason, veterinarians will usually
try to keep an animal with a chronic illness on low doses, or intermittent
doses (eg every other day instead of daily treatment) to minimise the
chances of side-effects developing. Because giving corticosteroids reduces the
production of natural corticosteroids by the adrenal glands animals should be
weaned off the drugs slowly so that the adrenals can gradually increase their
production.
Updated October 2013
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