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This information is provided by Provet for educational purposes only.

You should seek the advice of your veterinarian if your pet is ill as only he or she can correctly advise on the diagnosis and recommend the treatment that is most appropriate for your pet.

Drugs rarely have medicinal licenses for use in rabbits, and yet veterinarians have to prescribe them for their everyday treatment. Here is a list of suggested dose rates for commonly used drugs. 

The table has been derived from several published sources, and not all drugs are available in all countries. Different sources often vary greatly in their recommendations and caution should be exercised when administering high doses to rabbits.  Whenever possible veterinarians should use drugs that are licensed in their country for use in rabbits, and they should follow the manufacturers current data sheet recommendations.. Provet can not accept liability for any errors or omissions and readers are advised to check dose rates with drug manufacturers or recognised specialists in rabbit medicine before proceeding to administer them.

Administration Codes :

IM - intramuscular injection

IP - intraperitoneum injection

IV - intravenous injection

SC - subcutaneous injection

Rabbits are highly susceptible to some antibiotics and the following types are NOT recommended because they can cause a fatal gastrointestinal damage with enterotoxaemia. :

  • Ampicillin
  • Clindamycin
  • Erythromycin
  • Lincomycin
  • Penicillin
  • Streptomycin

Drug Name Source 1 Source 2 Source 3 Source 4 Clinical Indications
Acepromazine (acetylpromazine) 1-5 mg/kg  IM 1mg/kg IM 1-2mg/kg IM   Sedative or pre-anaesthetic drug
Acetylsalicylic acid (Aspirin) 500mg/kg/day orally       Analgesic, antipyretic anti-inflammatory drug
Alphaxalone/alphadolone   6-9mg/kg IV   12mg/kg IM (sedation)

6-9mg/kg IV

Atipamezole   1mg/kg SC, IM, IV, IP     Reverse medetomidine sedation
Amikacin 10mg/kg 2-3x daily SC or IM       Aminoglycoside antibiotic. Can induce acute renal failure especially in dehydrated animals, animals with renal disease or electrolyte imbalances
Ampicillin       200mg/kg/day orally in divided doses

25mg/kg/day IM

Amprolium 9.6% solution 1cc/7kg/day orally for 5 doses       Coccidiosis
Atropine 0.1-0.5mg/kg SC or IM 50 micrograms/kg SC, IM 10mg/kg every 20 mins  SC (for poisoning)

0.1-0.3mg/kg SC (for respiratory stimulation)

  Used in the treatment of organophosphate poisoning . However, many rabbits have atropinesterase in their circulation so atropine may be ineffective 
Buprenorphine   50 micrograms/kg SC, IV     Analgesia
Butorphanol   100-500 micrograms/kg SC or IV     Analgesia
Carbaryl 5% powder Light dust once/week        Insecticide. Low doses may inhibit breeding.
Carprofen   1.5mg/kg twice daily orally     Anti-inflammatory and analgesic
Cefalexin   15mg/kg twice daily SC     Antibiotic - a cephalosporin. Avoid in patients with renal disease
Cephaloridine       30mg/kg/day IM Antibiotic
Chloramphenicol palmitate 50mg/kg twice daily orally 50mg/kg/day orally 50mg/kg/day for up to 7 days orally   Antibiotic. Inappetance is a common side-effect in rabbits
Chloramphenicol succinate 30-50mg/kg twice daily SC or IM 50mg/kg twice daily SC  30mg/kg/day for up to 7 days IM 30mg/kg IM Antibiotic. Inappetance is a common side-effect in rabbits
Chlorpromazine     3-5mg/kg IV

3-35mg/kg IM

  Tranquilliser, anti-emetic
Chlortetracycline 50mg/kg twice daily orally 1g/L drinking water     Antibiotic. High calcium, magnesium or iron supplemented diets may inhibit the absorption of this drug.
Cimetidine 5-10mg/kg 2-4x daily       Inhibits gastric secretion
Clopidol   200g/tonne food     Coccidiosis
Dexamethasone   0.5-2 mg/kg SC, IM, IV     Anti-inflammatory
Diazepam 1mg/kg IP 1-2mg/kg IM, IV 5-10mg/kg IM   Sedative and pre-anaesthetic agent (used with ketamine)
Dichlorvos     500mg/kg food for 24 hours   Antiparasitic
Dichlorvos strip Hang in room for 24hrs once a week for 6 weeks   Leave in cage for 48 hours repeat at 7 day intervals   Antiparasitic - hung as strips in the environment to kill arthropod parasites eg chyletiella
Dimetridazole 0.2mg/ml drinking water       Antimicrobial. Clostridial enterotoxaemia in rabbits
Diovol plus 1-2cc orally       Antacid, anti-flatulant. Decreases gas production in gastrointestinal disorders. Do not use in rabbits with renal disease or alkalosis. Do not use with tetracyclines or iron compounds.
Dipyrone 6-12mg/kg 2-3x daily       Anti-inflammatory, antipyretic, analgesic and antispasmodic drug
Doxapram 2-5mg/kg IV 5-10mg/kg IV     Respiratory stimulant
Doxycycline 2.5mg/kg twice daily orally       Long-acting tetracycline which is efficient against anaerobes and intracellular bacteria. It is safer in animals with renal problems as it is excreted via the intestine.. 
Enrofloxacin 5mg/kg twice daily orally 50-100mg/L drinking water

5mg/kg twice daily orally or SC

    Fluoroquinolone antibiotic 
Fenbendazole 20mg/kg/day orally for 5 doses       Anthelminthic.
Fentanyl citrate /fluanisone   0.5ml/kg IM   0.2-0.5ml IM (sedation)

0.3ml/kg IM 

Fentanyl citrate /fluanisone/diazepam   0.3ml/kg IM and 2mg/kg IP or IV   0.3ml/kg IM and 1mg/kg Neuroleptanalgesia
Fentanyl citrate /fluanisone/midazolam   0.3ml/kg IM and 2ml/kg IP or IV   0.3ml/kg IM and 1mg/kg Neuroleptanalgesia
Flunixin   1.1mg/kg twice daily SC     Anti-inflammatory drug
Frusemide 5-10mg/kg twice daily       Diuretic
Gentamicin 5mg/kg/day SC or IM 4mg/kg/day IM     Aminoglycoside antibiotic especially effective against gram-negative organisms. May induce acute renal failure.
Griseofulvin 25mg/kg orally once daily for 28-40 days 25mg/kg/day orally for 28 days 25mg/kg/day for 4 weeks orally   Dermatophytosis
Halothane As required       General anaesthesia
Innovar-Vet 10% solution

(droperidol and fentanyl citrate) 

0.2-0.3ml/kg IM       Sedative and analgesic.  Used with xylazine for anaesthesia.
Isofluorane As required       Inhalant anaesthetic of choice for rabbits.
Ivermectin 200-400 micrograms/kg orally.  Two doses 8-10 days apart 200-400 micrograms/kg SC

400 micrograms/kg orally

200-400 micrograms/kg SC, IM   Antiparasiticide. Used to treat ear mites.
Ketamine 44mg/kg IP 50mg/kg IM 25-40mg/kg IM 25mg/kg IM (sedation)

10mg/kg IV (10 minutes after xylazine)

Dissociative anaesthetic. Irritant by IM route. Must be diluted and injected with care to avoid the sciatic nerve.
Ketamine and Diazepam 25mg/kg and 5mg/kg IP       Anaesthesia
Ketamine and Medetomidine   25mg/kg and 500micrograms /kg IP     Anaesthesia
Ketamine and Xylazine 35mg/kg and 5mg/kg IP 35mg/kg and 5mg/kg IM     Anaesthesia
Lime sulphur 2.5% solution Apply topically once a week for 4-6 weeks       Insecticide.
Lindane 0.03% solution Dip once a week for 3 treatments       Chlorinated hydrocarbon insecticide used to treat ectoparasites
Malathion 2% solution Dip every 10 days for 2 treatments       Organophosphate insecticide used to treat ectoparasites
Meperidine 10-20mg/kg/4x daily SC or IM       Short-acting narcotic analgesic
Methohexital   10mg/kg IV     Short-acting barbiturate anaesthesia
Methoxyfluorane As required       Anaesthesia
Metoclopramide 0.5mg/kg 3x daily SC 0.2-1mg/kg twice daily orally, SC, IM or IV     Anti-emetic. Used to treat gastric trichobezoars in rabbits. Should not be used if gastrointestinal obstruction, perforation or haemorrhage is present
Metronidazole 40mg/kg orally for 3 days       Antibiotic and antiprotozoal
Morphine 2-5mg/kg SC or IM every 4 hours 5mg/kg SC     Analgesia
Nalbuphine   1-2 mg/kg IV     Analgesia
Nalorphine     2mg/kg  IV   Reversal fentanyl 
Naloxone 0.01-0.1mg/kg IM or IV 0.01-0.1mg/kg IM, IP, IV     Reversal of narcotic toxicity
Neomycin 30mg/kg twice daily orally 200-800 mg/L drinking water     Aminoglycoside antibiotic. 
Oxytetracycline 50mg/kg twice daily orally

15mg/kg/day SC or IM 

30mg/kg twice daily orally

15mg/kg twice daily IM

  15mg/kg/day SC, IM 

30mg/kg SC or IM every 3 days (long acting preparation)

1mg/ml drinking water

55mg/kg/day in divided doses orally

Oxytocin 1 IU per rabbit IM   0.2-0.3 units/kg SC, IM   Induction of parturition and milk letdown
Pentazocine 10-20mg/kg SC every 4 hours 5mg/kg IV     Analgesia
Pentobarbital 20-40mg/kg IP 26mg/kg IV 35-45mg/kg IV, IP   Sedation and general anaesthesia. This is a high risk drug to use in rabbits.
Pethidine   10mg/kg SC, IM     Analgesia
Piperazine adipate 0.5g/kg/day for 2 doses 500 micrograms/kg/day. Repeat dose in 10 days     Anthelminthic
Piperazine citrate 100mg/kg/day for 2 doses   200mg/kg orally 200mg/kg orally Anthelminthic. Used to treat ascarids and some nodular worms and pin worms.
Praziquantel 5-10mg/kg orally, SC or IM . Repeat dose in 10 days.       Anthelminthic . Used to treat cestodes
Prednisone 0.5-2mg/kg orally       Anti-inflammatory glucocorticoid. Use with caution to avoid overdosage.
Procaine Penicillin G 20,000 - 60,000 IU/kg 3x daily   40,000 IU/kg/day for up to 7 days SC, IM   Antibiotic. Can induce altered gastrointestinal tract flora with overgrowth and  secondary enteritis.
Propofol   10mg/kg IV     Anaesthesia
Robenidine   50-66g/tonne food     Coccidiosis
Streptomycin   50mg/kg/day IM     Antibiotic
Sulphadimidine   100-233mg/L drinking water     Antibiotic. Coccidiosis.
Sulphamezathine 1-5mg/ml drinking water   1g/L drinking water for 5 days

1mg/ml drinking water for upto 60 days

  Antibiotic. Long term use can cause changes in gut flora and malnutrition - resulting in vitamin (eg vitamin K) deficiency.
Sulphaquinoxaline 1mg/ml drinking water   0.025% in drinking water for 30 days.

0.1% in drinking water for 14 days.

  Antibiotic for pasteurellosis and coccidiosis
T-61 0.3ml/kg IV       Euthanasia
Tetracycline 50mg/kg orally, 2-3x daily 30mg/kg twice daily orally 0.3-2mg/ml drinking water

5-50mg/kg orally, IM

  Antibiotic. For tyzzers disease, pasteurellosis, mycoplasmosis
Thiabendazole 50-100mg/kg/day orally for 5 days   100-200mg/kg 0.1% in food - orally   Anthelmintic, anti-inflammatory, antipyretic and fungicidal drug.
Thiamylal 30-40mg/kg IV   25-50mg/kg IV, IP   Ultra-short acting barbiturate anaesthesia
Thiopental 30-50mg/kg IP 30mg/kg/IV     Ultra-short acting barbiturate anaesthesia
Tresaderm (combination of thiabendazole, dexamethasone and neomycin) 3 drops into ear twice daily for a week       Chronic dermatoses and otitis externa eg psoroptes infection.
Trimethoprim and sulphadiazine 30mg/kg/day SC 48mg/kg/day SC     Antibiotic. 
Trimethoprim and sulphamethoxazole 15mg/kg twice daily orally       Antibiotic
Tylosin 10mg/kg twice daily orally , SC or IM   66mg/L drinking water for 21 days orally   Antibiotic. Chronic use can result in bacterial overgrowth in the large intestine.
Vetatix (pyrethrins and piperonyl butoxide) Shampoo weekly for up to 6 weeks       Insecticide (pyrethrin-based)
Viokase Give 2-3cc twice daily of the following mixture after 15 minutes standing : 1 teaspoon viokase to 3 tablespoons yoghurt       Pancreatic enzyme supplementation in EPI. In rabbits it is used to dissolve trichobezoars
Vitamin K 1-10mg/kg   1-10mg/kg   Vitamin K deficiency (eg following oral antibiotic use and malabsorption) or poisoning with vitamin K antagonists eg warfarin.
Xenodyne Swab as required       Antibacterial iodine solution
Xylazine     3-5mg/kg IM 3mg/kg IV Sedative, analgesia
Yohimbine 0.2mg/kg IV       Reversal of xylazine anaesthesia


Updated October 2013