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NATRIURETIC PEPTIDE AS AN EARLY MARKER OF HEART DISEASE IN DOGS First broadcast on www.provet.co.uk |
This information is provided by Provet for educational purposes only.
You should seek the advice of your veterinarian if your pet is ill as only he or she can correctly advise on the diagnosis and recommend the treatment that is most appropriate for your pet.
Atrial natriuretic peptide (ANP - a hormone) is secreted by the heart and the concentration of proANP (31-67) is an indicator of heart failure
It has been reported that serum or plasma atrial natriuretic peptide concentrations increase in canine heart failure. An immunoassay ELISA Test for proANP is available which can assist clinicians in the recognition of heart failure in dogs. The currently available test (VETSIGNTM Canine CardioSCREEN) requires 50ml serum or plasma per test.
The following results have been determined :
- proANP concentrations up to 1350 fmol/ml - NORMAL
- proANP concentrations 1350-1700 fmol/ml - SUSPECT range
- proANP concentrations over 1700 fmol/ml - 92% POSITIVE probability for heart failure
Last updated : October 2013