You should seek the advice of your veterinarian if your pet is ill as only he or she can correctly advise on the diagnosis and recommend the treatment that is most appropriate for your pet.

Abstract
Decreased elasticity of the cardiovascular system is one of the hallmarks of the normal aging process of mammals. A potential explanation for this decreased elasticity is that glucose can react nonenzymatically with long-lived proteins, such as collagen and lens crystallin, and link them together, producing advanced glycation endproducts (AGEs). Previous studies have shown that aminoguanidine, and AGE inhibitor, can prevent glucose cross-linking of proteins and the loss of elasticity associated with aging and diabetes. Recently, an AGE cross-link breaker (ALT-711) has been described, which we have evaluated in aged dogs. After 1 month of administration of ALT-711, a significant reduction (apprxeq40%) in age-related left ventricular stiffness was observed ((57.1 +- 6.8 mmHgcntdotm2/ml pretreatment and 33.1 +- 4.6 mmHgcntdotm2/ml posttreatment (1 mmHg = 133 Pa)). This decrease was accompanied by improvement in cardiac function.

Reference

PNAS: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA ,   97(6):2809-2813 2000     

Updated January 2016