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A
retrospective-cohort study on the development of cataracts in dogs with
diabetes mellitus: 200 cases.
Beam, Stacy, Correa, Maria T., Davidson, Michael G. Abstract
broadcast on www.provet.co.uk
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Abstract
The objective of the study was to determine the incidence and estimated median
time to cataract formation in dogs with diabetes mellitus. The animals studied
were 200 dogs with diabetes mellitus which were referred to a university
teaching hospital between 1985 and 1995. Medical records from dogs with a
diagnosis of diabetes mellitus were reviewed and, where necessary, further
follow-up information was gathered from the referring veterinarian. Incidence
rate and median time to diabetic cataract formation was calculated using
survival-analysis techniques in a retrospective cohort study design. Among the
200 dogs in the study population, 23 had cataracts at the time of diabetes
diagnosis that were presumed to be related to other disease processes. Of the
remaining 177 dogs, 132 had documented cataract development with features
suggestive as being secondary to diabetes. Twenty-three dogs did not have
obvious cataracts at the time of their last examination while 22 dogs did not
have cataracts at the time they were lost to follow-up. These 55 cases
contributed to the statistical models as noncases of cataracts until the last
date for which an examination was available. Half of the population had
developed cataracts by the 170th day postdiagnosis of diabetes mellitus, while
75% and 80% of the population developed cataracts by 370 days and 470 days,
respectively. The results of this study suggest that the majority of dogs with
diabetes will develop cataracts within 5-6 months from the time of diagnosis
of the disease, and that approximately 80% of dogs will develop cataracts
within 16 months of diagnosis.
Reference
VETERINARY OPHTHALMOLOGY , 2(3):169-172
1999
Updated January 2016
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