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This information is provided by Provet for educational purposes only. You should seek the advice of your veterinarian if your pet is ill as only he or she can correctly advise on the diagnosis and recommend the treatment that is most appropriate for your pet. The scientific
evidence to support the administration of nutritional supplements to pets is
often very weak. Best evidence are
randomised controlled trials (RCTs) Diet Restriction
Body weight control Nine papers relating to the relationship between diet
restriction and osteoarthritis met the inclusion criteria but these were all
generated from the same lifetime study of 48 Labrador retrievers, a breed
predisposed to develop OA. Restricting food consumption to 75% of
littermate’ s intake delayed the onset of OA after 5 years
(Kealy 1992; Kealy1997) and prevalence was 77% in the control group and
only 10% in the restricted intake group (Kealy 2000). Diet restriction delayed
OA by up to 5 years (Smith 2006), and at end of life the prevalence of hip OA
was 83% in the control group and 50% in the diet-restricted group. Further
studies in this cohort of dogs which involved periodic clinical assessment,
radiography, and at end of life gross examination and histological examination
of the joints showed that food restriction had little influence on the
development of OA in the elbow (Huck 2009) but it made a significant
difference to severity of OA in the shoulder (Runge 2008), and prevalence and
severity of OA in hips (Smith 2012; Smith 2006; Powers 2004). Appearance of
radiographic evidence of hip OA was delayed by 6 years in diet-restricted dogs
(median 12 years age) compared to the non-restricted group (median 6 years)
and the earliest change (circumferential femoral neck osteophyte (CFHO))
appeared at a median age of 3 years in non-restricted and 9 years in the
diet-restricted group (Szabo 2007). Evidence : GOOD -Positive effects for diet restriction References Huck JL, Biery DN, Lawler DF et al (2009) A longitudinal
study of the influence of lifetime food restriction on development of
osteoarthritis in the canine elbow. Vet Surg 38(2): 192-8 Kealy RD, Olsson SE, Monti KL et al (1992) Effects of
limited food consumption on the incidence of hip dysplasia in growing dogs. J
Am Vet Med Assoc 201: 857-863 Kealy RD et al. (1997) Five-year longitudinal study on
limited food consumption and development of OA in coxofemoral joints of dogs.
J Am Vet Med Assoc 210:222-5 Kealy RD, Lawler DF, Ballam JM et al.(2000) Evaluation of
the effect of limited food consumption on radiographic evidence of
osteoarthritis in dogs. J. Vet Med Assoc 217: 1678- 1680 Powers MY Biery DN, Lawler DF et al (2004) Use of the
caudolateral curvilinear osteophyte as an early marker for future development
of osteoarthritis associated with hip dysplasia in dogs.JAVMA 2004
225(2):233-7 Runge JJ, Biery DN, Lawler DF et al (2008) The effects of
lifetime food restriction on the development of osteoarthritis in the canine
shoulder. Veterinary Surgery 37(1): 102-7 Smith GK, Paster ER, Powers MY, et al (2006) Lifelong
diet restriction and radiographic evidence of OA of the hip joint in dogs. J
Am VetMed Assoc 229:690–693 Smith GK, Lawler DF, Biery DN et al. (2012) Chronology of
hip dysplasia development in a cohort of 48 Labrador retrievers followed for
life. Veterinary Surgery 41(1):20-33 Szabo SD, Biery DN, Lawler DF et al (2007) Evaluation of
circumferential femoral head osteophyte as an early indicator of
osteoarthritis characteristic of canine hip dysplasia in dogs JAVMA 2007
231(6):889-92 Updated September 2015 | |||