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GLYCOSURIA IN THE ABSENCE OF HYPERGLYCAEMIA

First broadcast on www.provet.co.uk  


This information is provided by Provet for educational purposes only.

You should seek the advice of your veterinarian if your pet is ill as only he or she can correctly advise on the diagnosis and recommend the treatment that is most appropriate for your pet.

Glucose should only appear in the urine of cats and dogs if blood glucose concentrations exceed the renal threshold of 8-11 mmol/l. However, on occasions clinicians find glucose in the urine when the blood glucose concentrations are normal.

The occurrence of glycosuria in the absence of hyperglycaemia is rare in both cats and dogs. .

 The following brief list should assist clinicians to determine possible causes :

  • Fanconi syndrome - defect in tubular transport  mainly seen in Basenjis (rare)
  • Idiopathic (primary) persistent glycosuria is occasionally seen in some breeds (suggesting a familial problem) - Cocker Spaniels, Norwegian Elkhounds.
  • Acute renal failure :
    • Due to nephrotoxins eg antibiotics
    • Due to obstruction
  • Poisoning
    • Lead
    • Organophosphates
  • Drug reaction
    • Phloridzin 
  • Chronic renal failure (extremely rare)

Last updated : January 2016