You should seek the advice of your veterinarian if your pet is ill as only he or she can correctly advise on the diagnosis and recommend the treatment that is most appropriate for your pet.

Fructosamine is useful in monitoring glycaemic stabilisation in diabetic dogs and cats

Fructosamine is a glycoprotein formed between glucose and albumin and measurement of serum fructosamine gives an indirect measure of the time-averaged glucose concentrations that albumin has been exposed to over the preceding period of 1-2 weeks.

This test is useful because it can be used to differentiate between chronic hyperglycaemia (due to diabetes mellitus) and transient hyperglycaemia - such as may occur with stress.

The normal range for serum fructosamine has been reported to be :

• Dogs - 250-350mmol/l
• Cats - 150-270mmol/l

Concentrations below 400mmol/l indicate good glycaemic control in treated diabetic dogs and cats, greater than 400mmol/l in cats and greater than 500mmol/l in dogs indicates poor glycaemic control or untreated diabetic animals. 

Fructosamine gives an indication of glucose levels over a 2-3 week period.  Fructosamine concentrations are approximately :

	Fructosamine values (micromol/l)
Dogs
Non-diabetic	225-365
Recently diagnosed	320-850
Treated - excellent control	350-400
Treated - good control	400-450
Treated - fair control	450-500
Treated - poor control	500+
Cats
Non-diabetic	190-365
Recently diagnosed	350-730
Treated - excellent control	350-400
Treated - good control	400-450
Treated - fair control	450-500
Treated - poor control	500+

Insulinoma in dogs may result in low fructosamine concentrations - ie below 250mmol/l.

Last updated : January 2016