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CYTOLOGICAL CHANGES IN
CANINE AND FELINE BRONCHOPULMONARY DISEASES First broadcast on www.provet.co.uk
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This information is provided by
Provet for educational purposes only.
You should seek the advice of your
veterinarian if your pet is ill as only he or she can correctly advise on the
diagnosis and recommend the treatment that is most appropriate for your pet.
Microscopic examination of samples
collected by bronchoalveolar lavage under general anaesthesia can help to give
a precise diagnosis in bronchopulmonary diseases of the cat and dog. The
following changes in cell content are recognised with different forms of
bronchopulmonary disease :
Cell Type |
Bacterial Disease |
Allergy |
Neoplasia |
Nucleated cells/ml |
N or moderate increase |
N to slight increase |
N to slight increase |
Macrophages |
N or slight increase |
N to slight increase |
N to slight increase |
Neutrophils |
Greatly increased .
Usually less than 5% |
N to slight increase |
N to slight increase |
Lymphocytes |
N to slight increase |
N to moderate increase |
N to slight increase |
Eosinophils |
N |
N to moderate increase
Usually less than 5% in dogs; less than 25% in cats. |
N to slight increase |
Other types of cell |
None |
Occasionally mast cells |
Neoplastic cells - not often
seen unless the cancer has invaded the bronchial tree. Usually carcinoma
or lymphosarcoma. |
N = normal numbers (low)
The main differential findings are highlighted
in red.
(adapted after Masserdotti C, Veterinaria (1998) Vol
12, p33-39) Last updated : January 2016
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