Rodenticide derived from red squill (Urginea scilla).
Animals most affected
Dogs, cats, (all species).
Etiology
Accidental ingestion of rat bait (either granular or in another form), containing
0.02-0.03% of scilliroside. (In theory the extract acts as an emetic, but this effect
does not occur in all animals.)
Toxicity
Digitalin-like cardiac glycoside.
Oral doses in mg/kg:
|
LD50
|
rats
|
0.4-2
|
|
|
chickens
|
400
|
|
LD
|
cattle
|
100-400
|
|
|
sheep
|
250
|
|
|
goats
|
500
|
|
|
dogs
|
145
|
|
|
cats
|
100
|
Clinical features
-
vomiting, diarrhoea;
-
weak pulse with bradycardia;
-
occasional hyperexcitability with cardiac arrhythmias;
-
ventricular fibrillation with a risk of ventricular block;
-
risk of death occurring in 2-3 days;
-
clinical signs may persist for 6-8 days.
Lesions
Non-specific:
-
gastroenteritis, occasionally haemorrhagic;
-
generalized congestion.
Treatment
-
oxygen therapy;
-
cardiac monitoring;
-
atropine (for ventricular block) sc or im,
-
do not use diuretics as any loss of potassium will exacerbate the toxicity.