Mycotoxins produced by Pithomyces chartarum.


[affected.gif] Animals most affected
Cattle, sheep.


[etiology.gif] Etiology
Ingestion of rye grass (Lolium species) contaminated by sporidesmin during autumn following periods of drought (particularly a problem in the south of France, Australia and New Zealand). Poisoning is still known as ‘ruminants' facial eczema'.


[toxic.gif] Toxicity
Sporidesmin causes photosensitivity secondary to hepatic damage.


[clinical.gif] Clinical features and lesions
These present 10-20 days following ingestion of the toxins:


[treatm~1.gif] Treatment
No antidote. Symptomatic care only:

[labinv~1.gif]
Laboratory investigations