A mycotoxin produced by Penicillium viridicatum, Aspergillus ochraceus, A. ostianus and other moulds.
Animals most affected
Dogs, pigs, poultry, cattle.
In cold climates, the fungi grow on rye, wheat, oat and corn, especially if the crop was damp on harvesting and stored damp.
The kidneys are most affected.
Toxic doses in ppm in the diet;
Oral doses in mg/kg ochratoxin A
the products of poisoned animals are considered unsafe to eat.
Clinical features and lesions
Reduced growth rate, dehydration, possibly ataxia, anaemia, catarrhal enteritis, acute nephrosis, hepatic necrosis.
Delayed sexual development, reduced egg laying and lowered fertility, yellow liver.
Retarded growth and delayed development, polydipsia, polyuria, renal oedema, regressive changes of the renal epithelium,with degeneration and hypertrophy.
Anorexia, diarrhoea, lowered milk production (in calves: presence of haemorrhages in the heart and serous membranes, nephritis).
Anorexia, vomiting, hyperthermia, polyuropolydipsia, dehydration, prostration and death may occur; purulent conjunctivitis, haemorrhagic enteritis, renal necrosis.
Symptomatic care only:
the distribution and feeding of contaminated or mouldy feedstuffs should be stopped immediately.