[affected.gif] Animals most affected
All species.


[etiology.gif] Etiology
Inhalation as a consequence of:

Note: poisoning is often associated with a human case (e.g. pets in the same room as owner).


[toxic.gif]
Toxicity

Causes anoxia in all tissues; the gas combines readily with the haemoglobin molecule in the blood to form carboxyhaemoglobin.
This process is difficult to reverse.

Toxicity is inversely proportional to the size of the animal involved; in order of decreasing sensitivity to CO:

birds > rodents > carnivores > man > cattle

Toxic doses for all animals are quoted as a % of the volume of air:
0.01% not dangerous if exposure is intermittent;
0.1% serious poisoning may result from exposure;
0.2% death within several minutes of exposure.



[clinical.gif] Clinical features
Acute intoxication

Chronic intoxication
(Rare), symptoms often vague or nonspecific:


[lesions.gif] Lesions


[treatm~1.gif] Treatment
Antidotes
Supply oxygen.

Symptomatic


[labinv~1.gif] Laboratory investigations
Take a blood sample to determine carboxyhaemoglobin.