Complex mycotoxin produced by several species of the fungus Fusarium (especially F. tricinctum).


[affected.gif] Animals most affected
Cattle, sheep, horses, poultry.


[etiology.gif] Etiology
The fungus, a plant pathogen, develops on cereals, which are then harvested and stored as hay or straw (in cold countries growth of the fungus is favoured by alternating hot and cold conditions). Poisoning results from ingestion of feed contaminated by the Fusarium species or their toxins.


[toxic.gif] Toxicity
The fusariotoxins (T2) belong to the tricothecene group of compounds which inhibit the incorporation of amino acids into proteins, causing fusariotoxicosis. In addition the toxins are irritant and corrosive to the skin and mucous membranes.
Toxic doses in mg/kg:
LD50 rats 4
  pigs 4
LD
cattle  
 
0.1 for 65 days


[clinical.gif] Clinical features
Acute form

The following symptoms have also been noted:
poultry
horses
calves

Chronic form
(Almost unknown):


[lesions.gif] Lesions


[treatm~1.gif] Treatment
Symptomatic care only: