[affected.gif] Animals most affected
All species.


[etiology.gif]
Etiology
Ingestion of forage contaminated by industrial pollution (incidence extremely rare). Deliberate or criminal poisoning is often referred to but is rarely seen in veterinary medicine.



[toxic.gif] Toxicity
Cumulative poison concentrating particularly in the CNS, the skin and all structures associated with the dermis/epidermis and ectodermis. Toxic doses not well known.


Sodium arsenite
LD 0.20.5 mg/kg per day for several months


Phenomenon of pseudo-tolerance, due to 'mithridatism', or gradual reduction in intestinal absorption.



[clinical.gif] Clinical features
Cutaneo-mucosal syndrome

Gastrointestinal effects

Neurological effects


[lesions.gif] Lesions


[treatm~1.gif] Treatment
Stop further exposure immediately.
Antidotes

Symptomatic



[labinv~1.gif] Laboratory investigations