(acute and subacute poisoning)

A heavy metal which is an irritant and cumulative poison.



[affected.gif] Animals most affected
Dogs, cattle, (wild birds, all animals).



[etiology.gif] Etiology
Accidental ingestion of arsenical agrochemical products (remaining in discarded containers), notably fungicides based on sodium arsenite (used on vines). Available commercially in the form of concentrated suspensions (up to 250 g/l).
Migrating and other wild birds are frequently killed either during spraying or immediately after application of the chemical to fields and open areas.
Accidental ingestion of ant killers based on organic arsenic salts. Several cases of criminal or deliberate poisoning have been reported.
Note. lead arsenate is still to be found on farms, although the chemical is no longer in use.



[toxic.gif] Toxicity
A highly toxic, thiol-depriving poison with a general irritant effect.
Oral doses (sodium arsenite):

LD all animals 5 25 mg/kg
LD in mg/animal:  
  horses 1000 - 3000
  cattle 1000 - 4000
  sheep, goats 250 - 500
  pigs 50 - 100
  dogs 50 - 150
  poultry 10 - 100






[clinical.gif] Clinical features
Acute poisoning

Subacute poisoning
Same clinical features as above but less pronounced with:


[lesions.gif] Lesions


[treatm~1.gif] Treatment
Antidotes

Symptomatic



[labinv~1.gif] Laboratory investigations