TABLE 1.2

Advantages and disadvantages of different vaccines

Advantages Disadvantages

Attenuated Systemic Several different ones available Original FCV vaccines based on strain F9. Most vaccines protect against majority of isolates, but not as well against all.

Convenient to administer Care needed with administration since if reaches oral/respiratory mucosa by mistake, can cause disease.

Should not generalise, but can do in some cases

Intranasal Induces better and more rapid (2-4 day)protection; useful for stray cat homes or during disease outbreak More difficult to administer Side effects of sneezing and sometimes other signs

May be useful in young kittens

Inactivated Systemic Convenient to administer Adjuvants may occasionally cause reaction

Safe in pregnant queens May not be such good immunity

Useful in virus free colonies

No reversion to virulence

	Advantages	Disadvantages
Attenuated Systemic	Several different ones available	Original FCV vaccines based on strain F9. Most vaccines protect against majority of isolates, but not as well against all.
	Convenient to administer	Care needed with administration since if reaches oral/respiratory mucosa by mistake, can cause disease.
		Should not generalise, but can do in some cases
Intranasal	Induces better and more rapid (2-4 day)protection; useful for stray cat homes or during disease outbreak	More difficult to administer Side effects of sneezing and sometimes other signs
	May be useful in young kittens
Inactivated Systemic	Convenient to administer	Adjuvants may occasionally cause reaction
	Safe in pregnant queens	May not be such good immunity
	Useful in virus free colonies
	No reversion to virulence