Treatment involves thorough debridement and cleansing
of the wound, and administration of intravenous or intramuscular penicillin G
(20 mg/kg twice daily ) least 5 days.
Prompt therapy with antitoxin has been recommended
intravenously (100-500 units/kg) or by local infiltration. However, as it does
not penetrate the CNS the efficacy of this therapy is debatable and there also
exists a risk of anaphylactic reactions to the antiserum.
Animals should be kept in a quiet and darkened room
and disturbed as little as possible as they may be hyperaesthetic.
Barbiturate or phenothiazine group drugs may be helpful
to control tetanic spasms. Diazepam (0.2 mg/kg IV as necessary) can be given
General nursing care is also important to empty the
bladder and rectum and to ensure adequate nutrition and hydration.
Nutritional support (enteral or parenteral) may be
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