Several anecdotal accounts and one well documented report exist of feline parapoxvirus (orf) infection. The condition appears to be less common than feline cowpox. In the best recorded case, the infected cat had multiple, crusty and scabbed skin lesions which healed after several weeks, and the cat had been in contact with goats. Diagnosis depends on electron microscopy of scabs as parapoxviruses are difficult to grow in cell culture.

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