Found world-wide (although very rare in UK), Babesia spp are spread by Ixodes ticks. Clinical signs depend on the age of dog (young animals are more susceptible) and the species and strain of parasite; they range from hyperacute haemolytic anaemia, shock and death, to acute haemolytic anaemia with haematuria and jaundice, and chronic weight loss. Parasites can be seen within erythrocytes. Treatments include diminazene aceturate (15 mg/kg, two subcutaneous injections given 24 hours apart), imidocarb diproprionate (6 mg/kg, subcutaneous or intramuscular) or intravenous trypan blue (10 mg/kg as 1% solution).
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