Dermatophytosis is often a self-limiting
disease, with recovery within months, so clipping and topical therapy may be all
that is required in many cases - especially since systemic therapy may be accompanied
by side effects.
In severe or chronic cases, the treatment
of choice is oral griseofulvin. The dose usually recommended for microsized formulations
is 15-20 mg/kg/day in cats, although some authors suggest higher doses of up to 150
mg/kg/day for both cats and dogs. Griseofulvin treatment should be continued until
at least 2 weeks after clinical recovery and until dermatophytes can no longer be
Ideally the animal should have all its
hair clipped, but, if this is not possible, then the areas around all lesions
must be clipped.
Clippings should be disposed of carefully
as they may be infectious to man.
Infected areas should be bathed to remove
scale, crusts or exudate and treated topically, for example with daily whole-body
baths in povidone iodine or chlorhexidine.
Griseofulvin is teratogenic and therefore
is contraindicated in pregnant animals.
Other side effects of griseofulvin include
vomiting, diarrhoea, anorexia, jaundice, anaemia, ataxia and depression.
Ketoconazole can be effective at treating
dermatophyte infections, but also has side effects, is relatively expensive,
and is not licensed for use in cats in the UK.
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