- Cat scratch disease and bacillary angiomatosis are human diseases.
- A.felis and B. henselae appear to cause no known disease in cats, although longer term studies suggested that cats can remain bacteraemic for at least 1 months.
Cat scratch disease
- Generally a benign, self-limiting disease, usually seen in children.
- Almost all patients with CSD have had contact with a cat or dog but around 30% have no apparent history of a cat scratch.
- Primary skin lesion, usually at the site of a recent scratch or wound
- first appears as a non-pruritic, erythematous papule;
- develops into a vesicle, then pustule;
- which ruptures, scabs over and heals.
- Regional lymphadenitis develops about a week after the skin lesion and may last several months.
- By the time the patient seeks medical help, lymphadenitis is often the only clinical sign.
- Atypical CSD (5-10% cases) includes:
- Perinaud's oculoglandular syndrome (after conjunctival inoculation):
- encephalitis (especially in adults);
- recurrent or suppurative lymphadenitis;
- systemic lesions (e.g. in the spleen).
- Bacillary angiomatosis is a disease mainly associated with HIV infection and characterised by multiple subcutaneous nodules.
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