Antibiotics are generally unable to penetrate abscess walls, but may be useful for
treating cellulitis and help prevent recurrence after drainage and other complications.
Second- or third-generation cephalosporins (e.g. cefoxitin at 10~20 mg/kg SC three
times daily), clindamycin (10 mg/kg orally twice daily) and metronidazole (10 mg/kg
orally three times daily) are second choice for their particular activity against
A single injection of penicillin C (25 mg/kg IM) given within 24 hours of being
bitten may help prevent cellulitis and abscess formation.
Penicillins and their derivatives such as ampicillin and amoxycillin (both at
20 mg/kg orally three times daily) are effective against most abscess-forming
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