In very young puppies include:
- soft stools progressing to diarrhoea;
- painful abdomen: the puppies cry continually with paddling limb movements until they die;
- sometimes dyspnoea; vomiting or salivation.
- Most puppies less than 2-3 weeks old die within 1 or 2 days of onset of clinical signs.
- Sudden death in very young puppies may be due to CHV infection.
- ‘Fading puppy syndrome'.
- Puppies over 2 weeks old seldom become severely ill, but may develop respiratory signs.
- Occasionally vesicular lesions on male and female genitalia in adults.
- Abortion or stillborn puppies from bitches infected during pregnancy.
- Most infection of adults is subclinical.
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