RABIES: Preventative vaccination for domestic animals

Originally live attenuated vaccines were used, but because of safety considerations they have now been largely superseded by inactivated vaccines. Primary vaccination is not generally recommended before 3 months of age, and should be followed by a booster 1 year later. Thereafter annual or triennial boosters should be given. One month should be allowed for the development of immunity. It should be remembered that fully vaccinated animals may in some cases still develop rabies. Recombinant (vaccinia and other poxvirus) vaccines have also recently been shown to be safe and efficacious in several species.

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