Note: The virus is labile, and therefore so is the vaccine when reconstituted with water (maximum 24 hours at 200C in dark - much less at higher temperatures and in daylight).

Measles virus is closely enough related to CDV that the immune response induced by measles vaccination may protect against distemper. But the two are antigenically sufficiently different that measles vaccination can provoke protective immunity in the presence of maternally-derived antibody to CDV. Therefore measles vaccine can be used in puppies at risk of infection from about 6 weeks of age. However, recent studies suggest that some modern distemper vaccines may be equally or even more effective at this age.

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