CPV-2 first appeared as a cause of a severe canine enteropathy and cardiomyopathy in 1978. Its origin is not clear. The original strain of CPV-2 has now been replaced worldwide by antigenic variants CPV-2a and/or CPV-2b.
- The virus has a world-wide distribution.
- Seroprevalence rates range from 25% for family-owned dogs to 90% for kennel dogs.
- CPV-2 is extremely hardy, and can survive in the environment for more than 6 months at room temperature, and thus may be transported over long distances by fomites.
- The main source of infection is faeces from infected dogs.
- Persistent or periodic faecal shedding from infected dogs does not appear to be a feature of CPV-2 infection because of the strong immune response mounted by infected dogs.
- Neither aerosol nor transplacental infection are thought to be important.
Back to menu