PATHOGENESIS AND PATHOLOGY: Campylobacteriosis
The reported incidence of Campylobacter
spp in dogs with or without diarrhoea varies
considerably, and many dogs are asymptomatic carriers. Thus the significance of Campylobacter
spp as a cause of gastrointestinal disease
not clear. The severity of disease is probably dependent upon the number of organisms
present, their ability to produce various toxins, previous exposure to Campylobacter
spp, the presence of other enteric pathogens and the development of protective antibody.
In general campylobacteriosis causes disease, and experimental infections are usually
less severe than field infections suggesting that other factors or organisms may
play a role in its pathogenesis.
Pathological findings of campylobacteriosis
Fluid colonic contents and thickening, congestion
and oedema of mucosa.
Decrease in enterocyte height and numbers
of goblet cells, and hyperplasia of epithelial glands. Villus height may be reduced.
Subepithelial congestion, haemorrhage and inflammation may be evident.
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