• Although several antibiotics may have some effect on relieving the clinical signs of chlamydial infection, tetracyclines remain the drugs of choice.
• As systemic infection has been demonstrated it is probably advisable to treat both systemically and topically.
• Ophthalmic ointment containing tetracycline should be applied 3-4 times daily. Currently only chlortetracycline is available in the UK.
• Oxytetracycline (20 mg/kg, 3 times daily) or doxycycline, a tetracycline derivative, (10 mg/kg, once a day), should be given systemically.
• All cats in the household should be treated simultaneously for at least 34 weeks or for at least 2 weeks after clinical signs have disappeared.
• Systemic tetracyclines are theoretically contraindicated in pregnant cats or in young kittens where there is calcification occurring. There is little evidence that treatment does, in fact, affect kittens' teeth but owners should be aware of the possibility.
• Erythromycin and tylosin may also be effective treatments, but no controlled trials have been carried out in cats.

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