fit or seizure results when there is a abnormal neuronal activity in the
cortex of the forebrain.
There are usually 4 clear phases in a fitting animal :
Careful observation of the prodromal phase is important because localised muscle twitching prior to the main seizure could indicate the presence of a local lesion within the brain, and so rule out a diagnosis of idiopathic epilepsy.
Clinical trials are currently being performed in humans on a device to alert about the onset of a fit - and this may be applicable to animals later.CLICK HERE
Several drugs are available to control epilepsy including :
Potassium bromide - used as a second-line drug
Imepitoin - recently launched first-line drug in dogs
Advantage - do not need to run blood analyses to titrate dose. Dose range of 10 mg to 30 mg imepitoin per kg bodyweight twice daily, approximately 12 hours apart
Other drugs that have been used in dogs include : Primidone -this is similar in it's actions to phenobarbitone, however there is a higher risk of developing liver failure; chlorazepate, valproic acid and clonazepam.
Animals on treatment should be re-examined by a veterinarian every few months to ensure that side-effects are not developing. Meticulous case recording is important to monitor on-going progress and response to treatment.
Sometimes a combination of two of the above drugs is needed to control the seizures.
If an animal is in status epilepticus the procedure is as follows :
Long term problems
Updated January 2016