Abnormal white cell morphology Abnormal white cell morphology

Abnormal white cells are sometimes seen on blood smears:

(1) Mast cells may occur in the circulation following trauma or acute inflammation, and also in the presence of mast cell tumours.
(2) Lymphoblasts are seen in lymphoproliferative diseases, e.g. leukaemia.
(3) Macrophages are seen in the presence of bacterial infection.
(4) Juvenile white blood cells are seen in association with myeloprolidiseases.
(5) Inclusion bodies may occur in lymphocytes, neutrophils or red blood cells following canine distemper virus infection. Various protozoa, fungi, and bacteria can be seen as intracellular infections - though most are rare in the UK.