Corticosteroids such as prednisone are used widely in the treatment of neoplasia
because they have antimitotic and cytolytic effects on lymphoid tissue as well as
anti-inflammatory and immunomodulating effects. They are particularly useful for
the treatment of lymphoproliferative disorders, mast cell tumours, and possibly brain
10-60 mq/m2 daily or on alternate davs.
Side-effects can include pancreatitis and gastrointestinal upsets and with long term
use suppression of adrenocortical function.