Immunomodulation Immunomodulation

Prednisone


Corticosteroids such as prednisone are used widely in the treatment of neoplasia because they have antimitotic and cytolytic effects on lymphoid tissue as well as anti-inflammatory and immunomodulating effects. They are particularly useful for the treatment of lymphoproliferative disorders, mast cell tumours, and possibly brain tumours.



Dose

10-60 mq/m2 daily or on alternate davs.


Side-effects can include pancreatitis and gastrointestinal upsets and with long term use suppression of adrenocortical function.