Inhibits protein synthesis. Cisplatin has been used in veterinary patients for the
treatment of osteosarcoma, soft tissue sarcoma and carcinomas.
by i.v. infusion 50-100mg/m2 over 15 minutes. Repeat 4-6 times
at 3-4 week intervals
Dogs should be fully hydrated and concomitant antiemetic and diuretic therapy are
Side-effects include nephrotoxicity, vomiting and myelosuppression. The risk of acute
renal tubular necrosis is so great with this drug that it should be used with extreme
caution in ageing animals, and it is contraindicated if renal impairment is present.